NCOA1 anticorps (AA 477-947)

N° du produit ABIN7466744

Cet anticorps anti-NCOA1 est un anticorps Souris Monoclonal détectant NCOA1 dans WB, IP et ChIP. Adapté pour Humain.

Aperçu rapide pour NCOA1 anticorps (AA 477-947) (ABIN7466744)

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCOA1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Clone: 1135

Détail du produit anti-NCOA1 anticorps

Épitope: AA 477-947

Réactivité croisée: Humain, Singe, Souris, Rat

Purification: Protein G purified

Immunogène: Amino acids 477-947 of human SRC-1.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. IP: 0.5 - 2 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: mouse brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur NCOA1

Antigène: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Autre désignation: nuclear receptor coactivator 1

Sujet: Nuclear receptor coactivator 1 , F-SRC-1 , KAT13A , RIP160 , SRC1 , bHLHe42 , bHLHe74,The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Poids moléculaire: 157 kDa

ID gène: 8648

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha